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    The Pharmaceutical Industry in South Africa 2025

    Carole Veitch | South Africa | 15 July 2025

    The Pharmaceutical Industry in South Africa 2023

    Gary Phillips | South Africa | 23 August 2023

    The Pharmaceutical Industry in South Africa 2022

    Carole Veitch | South Africa | 08 March 2022

    The Pharmaceutical Industry in South Africa 2020

    Carole Veitch | South Africa | 11 December 2020

    The Pharmaceutical Industry in South Africa 2019

    Ebhrahim Khalil | South Africa | 05 April 2019

    The Pharmaceutical Industry in South Africa 2017

    Ebrahim-Khalil Hassen | South Africa | 08 December 2017

    The Pharmaceutical Industry in South Africa 2016

    Ebrahim-Khalil Hassen | South Africa | 12 September 2016

    The Pharmaceutical Industry in South Africa 2014

    Amanda van der Westhuizen | South Africa | 30 May 2014

    Report Info

    Report Overview Report Summary Table of Contents
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    Report Coverage

    This report on the pharmaceutical industry in South Africa includes manufacturing, wholesale and retail, and provides information on the size and state of the industry in terms of the number of registered pharmacies and retailers, pharmaceutical sales and company performance. Issues such as National Health Insurance and the withdrawal of US funding are discussed, and there is information on notable players, corporate actions, regulations, technology, R&D and innovation. The report includes profiles of 92 companies such as major players Adcock Ingram and Aspen, international players operating in South Africa such as Cipla Medpro, Novartis, Pfizer and GlaxoSmithKline, and retailers such as Dis-Chem and Clicks.

    Introduction

    • South Africa\'s pharmaceutical industry, the largest and most advanced in sub-Saharan Africa, plays a critical role in the delivery of healthcare.
    • The industry is growing steadily, driven by research and development, innovation in biopharmaceuticals, public-private partnerships, and investment in local production.
    • The industry is preparing for supply chain disruptions resulting from international trade tensions.
    • Retail pharmacies play a crucial role in preventative care and the treatment of common illnesses.
    • Pharmacies are well-positioned to reach more patients and alleviate pressure on public primary healthcare providers.

    Trends

    • Continued shift to preventative healthcare, resulting in demand for vitamins, tonics, minerals, and supplements.
    • Focus on R&D, particularly radiopharmaceuticals, drugs, vaccines, and therapies targeting HIV/Aids, TB, malaria, cancer, chronic diseases, and obesity.
    • Growing focus on sustainability, including environmental, social and governance practices.
    • Growing pressure on pharmaceutical companies to make medicines more affordable.
    • Increased focus on localisation, including local production of APIs, and local manufacturing capacity.
    • Market concentration in the retail pharmacy sector is increasing, , with independent community pharmacies finding it difficult to compete with large wholesale-retail chains.

    Opportunities

    • Developing AI-driven diagnostics apps.
    • Pharmacies are increasingly offering value-added services, including instore clinics.
    • Pharmacies can partner with medical schemes on initiatives such as health-tracking apps.
    • Providing chronic medication collection services.
    • Providing in-pharmacy primary healthcare services.
    • Providing logistics and distribution services, including courier delivery services.
    • Retail pharmacies are increasingly aligning with wellness clinics, baby expos, sporting events, beauty salons, etc.
    • Strong R&D and advanced manufacturing capabilities may attract investment.
    • Supplying complementary medicines, including natural health products, traditional African medicine.
    • The development and manufacture of cannabis products.

    Challenges

    • Constrained public health spending on pharmaceuticals.
    • Continued margin pressure due to price regulation.
    • Counterfeit medications, expired drugs, and certain alternative remedies.
    • Funding challenges due to the withdrawal of US support for key health programmes.
    • Growing concentration of wholesale and retail pharmacy supply.
    • Medical scheme membership is stagnating, and essential medicines are unaffordable to most people.
    • South Africa’s dependence on imported active ingredients.
    • The abuse of OTC and prescription drugs.
    • The shortage of skilled professionals.
    • Trade tensions, higher tariffs, and global supply chain disruptions could drive up prices and lead to product shortages.
    • Uncertainties around the implementation of the NHI and its impact on the delivery of pharmaceuticals to the public and private sectors.

    Outlook

    • Industry growth is expected to be driven by the expansion of local manufacturing capacity, reducing the country’s reliance on imported products, and boosting exports.
    • The operating environment is expected to remain challenging.
    • Manufacturers and wholesalers are under pressure to reduce medicine prices.
    • Market concentration in the retail pharmacy sector is expected to increase.
    • Major retail players are expected to play an increasingly prominent role in primary healthcare.
    • Key risks include the effects of trade tensions which could disrupt supply chains and drive up prices.
    • There are opportunities for trade expansion, particularly in radiopharmaceuticals, medical cannabis, and biotechnology.

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    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2025

    Full Report

    R 20 000.00(ZAR) estimated $1132.11 (USD)*

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    Industry Landscape

    R 14 000.00(ZAR) estimated $ 792.48 (USD)*

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    Historical Reports

    The Pharmaceutical Industry in South Africa 2023-08-23

    R 6 500.00(ZAR) estimated $367.94 (USD)*

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    The Pharmaceutical Industry in South Africa 2022-03-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2020-12-11

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2019-04-05

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2017-12-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2016-09-12

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2014-05-30

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Value Chain 8
    2.2. Geographic Position 10
    2.3. Size of the Industry 12
    3. LOCAL 15
    3.1. State of the Industry 15
    3.2. Key Trends 23
    3.3. Key Issues 25
    3.4. Notable Players 25
    3.5. Trade 33
    3.6. Corporate Actions 35
    3.7. Regulations 38
    3.8. Enterprise Development and Social Development 41
    4. AFRICA 43
    5. INTERNATIONAL 47
    6. INFLUENCING FACTORS 53
    6.1. Unforeseen Events 53
    6.2. Economic Environment 53
    6.3. Labour 56
    6.4. Environmental Issues 58
    6.5. Technology, R&D, Innovation 60
    6.6. Government Support 63
    6.7. Input Costs 65
    6.8. Drug Abuse and Other Health Concerns 65
    7. COMPETITIVE ENVIRONMENT 66
    7.1. Competition 66
    7.2. Ownership Structure of the Industry 67
    7.3. Barriers to Entry 67
    8. INDUSTRY SUMMARY 68
    9. OUTLOOK 69
    10. INDUSTRY ASSOCIATIONS 69
    11. REFERENCES 70
    11.1. Publications 70
    11.2. Websites 71
    ANNEXURE 1 72
    Industry Legislation 72
    APPENDIX 1 81
    Summary of Notable Players 81
    APPENDIX 2 91
    HS Codes 91
    COMPANY PROFILES 92
    ABBOTT LABORATORIES SOUTH AFRICA (PTY) LTD 92
    ACINO HEALTHCARE GROUP (PTY) LTD 94
    ADCOCK INGRAM HOLDINGS LTD 96
    AFRICAN MEDICINES (PTY) LTD 101
    AFRIGEN BIOLOGICS (PTY) LTD 103
    AFRIPLEX (PTY) LTD 105
    AIM AFRICA (BRANCH OF AIM INTERNATIONAL INC) 108
    ALPHA PHARM (PTY) LTD 110
    AMWAY SOUTH AFRICA (PTY) LTD 113
    ARRIE NEL PHARMACY GROUP (PTY) LTD 115
    ASCENDIS HEALTH LTD 117
    ASPEN PHARMACARE HOLDINGS LTD 122
    ASTELLAS PHARMA (PTY) LTD 128
    ASTRAZENECA PHARMACEUTICALS (PTY) LTD 130
    AUROBINDO PHARMA (PTY) LTD 132
    AUSTELL PHARMACEUTICALS (PTY) LTD 134
    B BRAUN MEDICAL (PTY) LTD 136
    BARRS PHARMACEUTICALS INDUSTRIES (PTY) LTD 139
    BAXTER HEALTHCARE SOUTH AFRICA (PTY) LTD 140
    BAYER (PTY) LTD 142
    BECTON DICKINSON (PTY) LTD 146
    BIO EARTH MANUFACTURING (PTY) LTD 148
    BIOLOGICALS AND VACCINES INSTITUTE OF SOUTHERN AFRICA (PTY) LTD (THE) 150
    CALIFORNIA PHARMACEUTICALS (PTY) LTD 152
    CFAO HEALTHCARE SOUTH AFRICA (PTY) LTD 154
    CILO CYBIN PHARMACEUTICAL (PTY) LTD 156
    CIPLA MEDPRO SOUTH AFRICA (PTY) LTD 158
    COMED HEALTH (PTY) LTD 161
    DEON SCHOEMAN CC 163
    DIS-CHEM PHARMACIES LTD 166
    DR REDDY\'S LABORATORIES (PTY) LTD 179
    DSV SOLUTIONS (PTY) LTD 181
    EVOHEALTH (PTY) LTD 183
    FERRING (PTY) LTD 185
    FOREVER LIVING PRODUCTS SOUTH AFRICA (PTY) LTD 186
    FRESENIUS KABI MANUFACTURING SA (PTY) LTD 189
    FRESENIUS KABI SOUTH AFRICA (PTY) LTD 191
    GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD 194
    GLENMARK PHARMACEUTICALS SOUTH AFRICA (PTY) LTD 196
    GULF DRUG COMPANY (PTY) LTD 198
    H H DURRHEIM (PTY) LTD 200
    HEALTH AND HOME PHARMACY (PTY) LTD 202
    HERBA ZONE (PTY) LTD 203
    HERBALIFE INTERNATIONAL SOUTH AFRICA LTD (BRANCH OF HERBALIFE INTERNATIONAL) 205
    HERSOL MANUFACTURING LABORATORIES (PTY) LTD 207
    INFECTION PROTECTION PRODUCTS (PTY) LTD 209
    INGELHEIM PHARMACEUTICALS (PTY) LTD 211
    KENVUE SA (PTY) LTD 213
    LAKATO (PTY) LTD 215
    LOCAL CHOICE (PTY) LTD (THE) 217
    MEDCAN (PTY) LTD 219
    MERCK (PTY) LTD 220
    MSD (PTY) LTD 222
    NATIONAL BIOPRODUCTS INSTITUTE NPC 224
    NATIVA (PTY) LTD 226
    NEOLIFE INTERNATIONAL (PTY) LTD 228
    NESTLE (SOUTH AFRICA) (PTY) LTD 230
    NETCARE PHARMACIES (PTY) LTD 233
    NETCARE PHARMACIES 2 (PTY) LTD 235
    NEW CLICKS SOUTH AFRICA (PTY) LTD 237
    NKUNZI PHARMACEUTICALS (PTY) LTD 241
    NOVARTIS SOUTH AFRICA (PTY) LTD 243
    ORGANON SOUTH AFRICA (PTY) LTD 245
    OSIRIS HEALTHCARE (PTY) LTD 247
    P AND G SOUTH AFRICAN TRADING (PTY) LTD 248
    PARCEVAL (PTY) LTD 250
    PFIZER LABORATORIES (PTY) LTD 252
    PHARMA DYNAMICS (PTY) LTD 254
    PHARMACEUTICAL ENTERPRISES (PTY) LTD 256
    PHARMACY DIRECT (PTY) LTD 258
    PHARMACYWEB HOLDINGS (PTY) LTD 260
    PHARMAFORCE (PTY) LTD 261
    PHARMED PHARMACEUTICALS (PTY) LTD 263
    PICK N PAY STORES LTD 265
    RANBAXY (S A) (PTY) LTD 285
    RANBAXY PHARMACEUTICALS (PTY) LTD 287
    RECKITT BENCKISER PHARMACEUTICALS (PTY) LTD 289
    RELEAF PHARMACEUTICALS (PTY) LTD 291
    ROCHE PRODUCTS (PTY) LTD 293
    S A NATURAL PRODUCTS (PTY) LTD 296
    S BUYS (PTY) LTD 298
    SAFARMEX (PTY) LTD 301
    SANDOZ SOUTH AFRICA (PTY) LTD 303
    SANOFI-AVENTIS SOUTH AFRICA (PTY) LTD 305
    SHOPRITE HOLDINGS LTD 307
    SONKE PHARMACEUTICALS (PTY) LTD 408
    SOUTH AFRICAN NUCLEAR ENERGY CORPORATION LTD (THE) 410
    SPAR GROUP LTD (THE) 414
    TRANSPHARM (PTY) LTD 487
    VIATRIS SOUTH AFRICA (PTY) LTD 489
    VITAL HEALTH FOODS (PTY) LTD 491
    WACO AFRICA (PTY) LTD 493
    WELLNESS WAREHOUSE (PTY) LTD 496
    WOOLWORTHS HOLDINGS LTD 500

    Report Coverage

    This report on the pharmaceutical industry in South Africa provides comprehensive information on the manufacturing, wholesale and retail subsectors, price regulation, medical cannabis, market shares, notable multinational and local players and corporate actions. There are profiles of 128 companies including local dominant players Aspen Pharmacare and Adcock Ingram, multinationals such as Bayer, GlaxoSmithKline and Pfizer and retailers Clicks and Dis-Chem and other players such as Nativa.

    Introduction

    • More than 80% of South African pharmaceutical manufacturing and distribution revenue is from the private sector.
    • State purchases of pharmaceuticals are declining, and manufacturers’ margins are under pressure due to low regulated price increases for scheduled pharmaceuticals in a high inflation environment.
    • In the retail sector Clicks and Dis-Chem have wholesale volume advantages and an ever-increasing footprint.
    • Consumer spending patterns have forced consolidation in the retail sector, the growth of private label sales, growth in convenience formats, and diversification into new services and products.
    • There has been a flurry of investments in localising vaccine raw material and finished dose manufacturing, although the sustainability of these initiatives is far from secure.

    Trends

    • A shift from reactive medicine to preventative healthcare resulting in demand for immunity-building vitamins, tonics, minerals and supplements.
    • Focus on research and development, particularly drugs and therapies targeting COVID-19, HIV/Aids, TB, malaria, cancer, and chronic diseases.
    • Growing pressure on pharmaceutical companies to improve access to healthcare by making medicines more affordable.
    • Increased focus on localisation, including local sourcing of inputs and the development of local manufacturing capacity.
    • Recovery of demand as elective surgery and procedures and illnesses such as flu return to pre-pandemic patterns.
    • Small community pharmacies are finding it difficult to compete with large retail businesses.

    Opportunities

    • Cannabis cultivation, processing and medical product manufacturing.
    • Rapid growth in generic sales making medicine more affordable.
    • Strong R&D and advanced manufacturing capabilities may attract investment-.

    Challenges

    • Growing concentration of wholesale and retail pharmacy supply.
    • Low regulated medicine price increases in the context of high international inflation.
    • Poor economic growth constraining consumer spending on healthcare.
    • Reduced government budgets for medicines restricting local opportunities in the face of cheaper international competition.
    • South Africa’s dependence on imported active ingredients.
    • Sustaining local vaccine manufacturing in the face of declining demand.

    Outlook

    • The pharmaceutical industry is well developed and supported by strong R&D and advanced manufacturing capabilities, including biotechnology manufacturing facilities.
    • The Department of Health’s affordable medicines programme has been instrumental in lowering scheduled pharmaceutical prices, particularly in the public sector.
    • Investments in vaccine manufacture have begun to address South Africa’s exposure to vulnerabilities and dependence on active pharmaceutical ingredient and vaccine imports.
    • These investments have strengthened South Africa’s position as the hub for sub-Saharan African pharmaceutical research, development, and supply.
    • However, vaccine demand has dropped and doses are being donated to African countries.
    • Margin pressure is expected to grow as the economy remains poor and restraints on consumer spending intensify.
    • The implementation of the National Health Insurance is likely to put further pressure on manufacturers and wholesalers to reduce medicine prices.

    Read More..
    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2023

    Full Report

    R 6 500.00(ZAR) estimated $367.94 (USD)*

    Buy Now +

    Industry Landscape

    R 4 550.00(ZAR) estimated $ 257.56 (USD)*

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    Historical Reports

    The Pharmaceutical Industry in South Africa 2025-07-15

    R 20 000.00(ZAR) estimated $1132.11 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2022-03-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2020-12-11

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2019-04-05

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2017-12-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2016-09-12

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2014-05-30

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Value Chain 9
    2.2. Geographic Position 10
    2.3. Size of the Industry 11
    3. LOCAL 17
    3.1. State of the Industry 17
    3.2. Key Trends 22
    3.3. Key Issues 23
    3.4. Notable Players 24
    3.5. Trade 34
    3.6. Corporate Actions 36
    3.7. Regulations 38
    3.8. Enterprise Development and Social Development 43
    4. AFRICA 45
    5. INTERNATIONAL 50
    6. INFLUENCING FACTORS 57
    6.1. Unforeseen Events 57
    6.2. Economic Environment 58
    6.3. Labour 60
    6.4. Environmental Issues 62
    6.5. Technology, R&D, Innovation 63
    6.6. Government Support 65
    6.7. Input Costs 67
    6.8. Drug Abuse and Other Health Concerns 68
    7. COMPETITIVE ENVIRONMENT 68
    7.1. Competition 68
    7.2. Ownership Structure of the Industry 70
    7.3. Barriers to Entry 70
    8. INDUSTRY SUMMARY 71
    9. OUTLOOK 72
    10. INDUSTRY ASSOCIATIONS 72
    11. REFERENCES 73
    11.1. Publications 73
    11.2. Websites 74
    APPENDIX 1 75
    Summary of Notable Players 75
    COMPANY PROFILES 89
    Abbott Laboratories South Africa (Pty) Ltd 89
    Acino Healthcare Group (Pty) Ltd 91
    Adcock Ingram Holdings Ltd 93
    African Medicines (Pty) Ltd 98
    Afrigen Biologics (Pty) Ltd 100
    Afriplex (Pty) Ltd 102
    AIM Africa 105
    Alpha Pharm (Pty) Ltd 107
    Amka Products (Pty) Ltd 109
    Amway South Africa (Pty) Ltd 112
    Arrie Nel Pharmacy Group (Pty) Ltd 114
    Ascendis Health Ltd 116
    Aspen Pharmacare Holdings Ltd 121
    Astellas Pharma (Pty) Ltd 127
    AstraZeneca Pharmaceuticals (Pty) Ltd 129
    Aurobindo Pharma (Pty) Ltd 131
    Austell Pharmaceuticals (Pty) Ltd 133
    B Braun Medical (Pty) Ltd 135
    Barrs Pharmaceuticals Industries (Pty) Ltd 138
    Baxter Healthcare South Africa (Pty) Ltd 140
    Bayer (Pty) Ltd 142
    Becton Dickinson (Pty) Ltd 145
    Bio Earth Manufacturing (Pty) Ltd 147
    Biologicals and Vaccines Institute of Southern Africa (Pty) Ltd (The) 149
    Bitek Industries (Pty) Ltd 151
    California Pharmaceuticals (Pty) Ltd 153
    Caprichem (Pty) Ltd 155
    Chemical Convertors (Pty) Ltd 157
    Chemtron Holdings (Pty) Ltd 158
    Cilo Cybin Pharmaceutical (Pty) Ltd 160
    Cipla Medpro South Africa (Pty) Ltd 162
    Columbia Pharmaceuticals (Pty) Ltd 165
    CoMED Health (Pty) Ltd 167
    Deon Schoeman CC 169
    Dis-Chem Pharmacies Ltd 172
    Dr Reddy\'s Laboratories (Pty) Ltd 184
    DSV Solutions (Pty) Ltd 186
    Dynachem (Pty) Ltd 188
    Ecolab (Pty) Ltd 190
    Eli Lilly (S A) (Pty) Ltd 192
    Evohealth (Pty) Ltd 194
    Felbridge (Pty) Ltd 196
    Ferring (Pty) Ltd 198
    Forever Living Products South Africa (Pty) Ltd 200
    Fresenius Kabi Manufacturing SA (Pty) Ltd 203
    Fresenius Kabi South Africa (Pty) Ltd 205
    G M Pharmaceuticals (Pty) Ltd 208
    GlaxoSmithKline South Africa (Pty) Ltd 210
    Glenmark Pharmaceuticals South Africa (Pty) Ltd 213
    Goodleaf Company (Pty) Ltd (The) 215
    Gulf Drug Company (Pty) Ltd 217
    H H Durrheim (Pty) Ltd 219
    Herba Zone (Pty) Ltd 221
    Herbalife International South Africa Ltd 223
    Hersol Manufacturing Laboratories (Pty) Ltd 225
    Hymed (Pty) Ltd 227
    IMBC Investment (Pty) Ltd 229
    iMvula Healthcare Logistics (Pty) Ltd 231
    Infection Protection Products (Pty) Ltd 233
    Ingelheim Pharmaceuticals (Pty) Ltd 235
    Iszipharm Pharmaceutical Distributors (Pty) Ltd 237
    Joe Soap CC 239
    Johnson and Johnson (Pty) Ltd 241
    Kellogg Company of South Africa (Pty) Ltd 243
    Kevali Chemical Group (Pty) Ltd 245
    Lakato (Pty) Ltd 247
    Leaf Botanicals (Pty) Ltd 249
    MedCan (Pty) Ltd 250
    Medichem (Pty) Ltd 251
    Mega Magic CC 252
    Merck (Pty) Ltd 254
    MSD (Pty) Ltd 256
    National Bioproducts Institute NPC 258
    Nativa (Pty) Ltd 260
    NeoLife International (Pty) Ltd 262
    Nestle (South Africa) (Pty) Ltd 264
    Netcare Pharmacies (Pty) Ltd 268
    Netcare Pharmacies 2 (Pty) Ltd 270
    New Clicks South Africa (Pty) Ltd 272
    Nkunzi Pharmaceuticals (Pty) Ltd 276
    Novartis South Africa (Pty) Ltd 278
    Omnia Holdings Ltd 280
    Organon South Africa (Pty) Ltd 286
    P and G South African Trading (Pty) Ltd 288
    Parceval (Pty) Ltd 290
    Pfizer Laboratories (Pty) Ltd 292
    Pharma Dynamics (Pty) Ltd 295
    Pharmaceutical Enterprises (Pty) Ltd 297
    Pharmacy Direct (Pty) Ltd 299
    Pharmacyweb Holdings (Pty) Ltd 301
    PharmaForce (Pty) Ltd 302
    Pharmed Pharmaceuticals (Pty) Ltd 304
    Pick n Pay Stores Ltd 306
    Platchem (Pty) Ltd 311
    Prime Cleaning Suppliers (Pty) Ltd 312
    Ranbaxy (S A) (Pty) Ltd 314
    Ranbaxy Pharmaceuticals (Pty) Ltd 316
    Reckitt Benckiser Pharmaceuticals (Pty) Ltd 318
    Releaf Pharmaceuticals (Pty) Ltd 320
    Richbay Chemicals (Pty) Ltd 322
    Roche Products (Pty) Ltd 324
    S A F I C (Pty) Ltd 327
    S A Natural Products (Pty) Ltd 329
    S Buys (Pty) Ltd 331
    Safarmex (Pty) Ltd 334
    Safety Chemicals (Pty) Ltd 336
    Sandoz South Africa (Pty) Ltd 337
    Sanofi Industries South Africa (Pty) Ltd 339
    Sanofi-Aventis South Africa (Pty) Ltd 341
    Shoprite Holdings Ltd 344
    Solgar South Africa (Pty) Ltd 349
    Sonke Pharmaceuticals (Pty) Ltd 351
    South African Nuclear Energy Corporation SOC Ltd (The) 353
    SPAR Group Ltd (The) 357
    Specialised Maintenance Products (Pty) Ltd 362
    Specpharm Holdings (Pty) Ltd 363
    Spectank (Pty) Ltd 365
    Tevo (Pty) Ltd 368
    Tiger Brands Ltd 370
    Topmed Health Care Distributors (Pty) Ltd 375
    Touchless Germ Control Western Cape CC 377
    Transpharm (Pty) Ltd 378
    Unilever South Africa (Pty) Ltd 380
    Viatris South Africa (Pty) Ltd 383
    Vital Health Foods (Pty) Ltd 385
    Waco Africa (Pty) Ltd 387
    Wellness Warehouse (Pty) Ltd 391
    Woolworths Holdings Ltd 395

    Report Coverage

    This report focuses on the pharmaceutical industry in South Africa including manufacture, retail and wholesale trade in pharmaceuticals and alternative health products, such as medicinal cannabis. The report includes information on the state and size of the industry, notable players in each subsector, developments, corporate actions, regulations and other influencing factors. There are profiles of 129 companies including international companies Cipla, Novartis, Johnson & Johnson and Pfizer, local companies including Aspen and Adcock Ingram, retailers Clicks and Dis-Chem, and cannabis companies such as Goodleaf.

    Introduction

    The importance of the pharmaceutical industry has been amplified by the COVID-19 pandemic and the resulting global health crisis. The sector, which generated total sales revenue of around R60.4bn in 2021, has been designated as a strategic industry as it produces and supplies essential products. South Africa has the world’s largest antiretroviral (ARV) programme and is one of the major producers of radiopharmaceuticals . With the ongoing development of local manufacturing capacity and capabilities, local pharmaceutical companies are set to play a pivotal role in the production and supply of COVID-19 vaccines and other medicines for the domestic market and the rest of Africa. This report also examines the wholesale and retail trade in pharmaceuticals and alternative health products, such as medicinal cannabis. In 2021, government unveiled a cannabis master plan that aims to expand the country’s nascent cannabis industry, attract foreign investment and create up to 25,000 jobs. While cannabis is widely touted as a panacea, medical scientists caution that there is still a lack of reliable evidence to support claims about its medical efficacy.

    Strengths

    • South Africa has the largest antiretroviral (ARV) treatment programme in the world and almost half of the people infected with HIV/Aids in South Africa are on ARVs.
    • South Africa is one of the world’s largest producers of radiopharmaceuticals.
    • South Africa is the only Southern African Development Community member country that complies with the World Health Organisation’s Good Manufacturing Practice standards.
    • The industry is supported by strong research and development capabilities and advanced manufacturing capabilities, including biotechnology manufacturing facilities.
    • The presence of several of the world’s largest pharmaceutical companies supports research and product development.

    Weaknesses

    • Although pharmaceuticals are strictly regulated, over-the-counter medications and prescription drugs are widely misused and abused.
    • Inadequate quality control of CBD products, hand sanitisers and other hygiene products.
    • The cost of medicinal products, particularly newly developed treatments such as cell and gene therapies, is high.
    • There are around 30 pharmacists per 100,000 people, well below the global benchmark of 50 per 100,000.
    • There is an overreliance on imported active pharmaceutical ingredients and certain finished medicinal products.

    Opportunities

    • Advances in 3D printing have made the production of small batches of tablets viable.
    • As the Department of Health expands its chronic medication delivery and collection services programme, greater collaboration between the public health sector and pharmacies is anticipated.
    • Government has identified the pharmaceutical industry as a strategic sector and it supports the procurement of locally-manufactured products.
    • National Health Insurance offers opportunities for private sector community
    • Participation of retail pharmacies in the national vaccination programme.
    • pharmacies to provide primary care services to public health patients.
    • Strong demand for home delivery services is driving the expansion of courier pharmacy networks.
    • The development and manufacture of active pharmaceutical ingredients.
    • The development of traditional/indigenous medicines.
    • The development, production and supply of health products containing cannabidiol, such as CBD oil.
    • The supply of healthcare products via online and mobile retail channels.
    • The supply of sanitising products and disinfectants locally and to the rest of Africa.
    • With free trade between African counties underway, South Africa is aiming to expand its pharmaceutical exports into the rest of Africa.

    Threats

    • Climate-change related shocks.
    • Counterfeit medication and substandard products pose health risks.
    • Further reputational damage resulting from the misuse/abuse of prescription drugs.
    • Global supply chain disruptions.
    • Misinformation spread via social media and other channels about vaccinations and unproven remedies.
    • New COVID-19 variants and the outbreak of other pandemics.
    • Social unrest.
    • Sustained economic pressures could result in funding constraints.
    • The emergence of drug-resistant super bugs.

    Outlook

    The pandemic has brought into sharp focus the critical need for access to vaccines and affordable medicines. The gridlocked global supply chain has highlighted the risks associated with South Africa’s over-reliance on imports for active pharmaceutical ingredients and essential drugs. While stakeholders have welcomed initiatives to boost domestic manufacturing capacity and capabilities, they say that South Africa needs to reduce its dependency on imported inputs. With free trade under the African Continental Free Trade Area Agreement underway, role players anticipate that South African pharmaceutical manufacturers will perform an increasingly important role in the provision of vaccines and other pharmaceutical products to the rest of Africa.In the retail space, analysts foresee continued expansion of ecommerce and other dispensing channels, such as pharmaceutical vending machines. Stakeholders say that the collaboration of private retail pharmacies with the Department of Health on the COVID-19 vaccination programme has proved highly successful and paves the way for future partnerships between the public and private sectors. While the pandemic presents opportunities for companies in the pharmaceutical value chain, analysts expect the operating environment to remain challenging over the medium-term. Analysts predict that the local medical cannabis industry will expand rapidly over the next five years. While some smaller cannabis businesses have reservations about large pharmaceutical companies dominating the market, others say that the industry has been given a “shot in the arm” by government’s cannabis master plan.

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    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2022

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    The Pharmaceutical Industry in South Africa 2025-07-15

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    The Pharmaceutical Industry in South Africa 2023-08-23

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    The Pharmaceutical Industry in South Africa 2020-12-11

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    The Pharmaceutical Industry in South Africa 2019-04-05

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    The Pharmaceutical Industry in South Africa 2017-12-08

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    The Pharmaceutical Industry in South Africa 2016-09-12

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    The Pharmaceutical Industry in South Africa 2014-05-30

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Value Chain 10
    2.2. Geographic Position 11
    2.4. Key Success Factors and Pain Points 18
    3. LOCAL 19
    3.1. Key Trends 22
    3.2. Notable Players 24
    3.3. Trade 27
    3.4. Corporate Actions 32
    3.5. Regulations 34
    3.6. Enterprise Development and Social Economic Development 40
    4. AFRICA 42
    5. INTERNATIONAL 49
    6. INFLUENCING FACTORS 56
    6.1. COVID -19 56
    6.2. Economic Environment 61
    6.3. Labour 62
    6.4. Environmental Issues 66
    6.5. Technology, Research and Development (R&D) and Innovation 67
    6.6. Government Support 69
    6.7. Drug Abuse and Other Health Concerns 71
    7. COMPETITIVE ENVIRONMENT 73
    7.1. Competition 73
    7.2. Ownership Structure of the Industry 74
    7.3. Barriers to Entry 75
    8. SWOT ANALYSIS 75
    9. OUTLOOK 77
    10. INDUSTRY ASSOCIATIONS 78
    11. REFERENCES 79
    11.1. Publications 79
    11.2. Websites 80
    APPENDICES 82
    Appendix 1 - Summary of Notable Players 82
    COMPANY PROFILES 95
    Abbott Laboratories South Africa (Pty) Ltd 95
    Acino Healthcare Group (Pty) Ltd 97
    Adcock Ingram Holdings Ltd 100
    African Medicines (Pty) Ltd 105
    Afrigen Biologics (Pty) Ltd 107
    Afriplex (Pty) Ltd 109
    AIM Africa 112
    Alpha Pharm (Pty) Ltd 114
    Amka Products (Pty) Ltd 117
    Amway South Africa (Pty) Ltd 120
    Arrie Nel Pharmacy Group (Pty) Ltd 122
    Ascendis Health Ltd 124
    Aspen Pharmacare Holdings Ltd 130
    Astellas Pharma (Pty) Ltd 136
    AstraZeneca Pharmaceuticals (Pty) Ltd 138
    Aurobindo Pharma (Pty) Ltd 140
    Austell Pharmaceuticals (Pty) Ltd 142
    B Braun Medical (Pty) Ltd 144
    Barrs Pharmaceuticals Industries (Pty) Ltd 147
    Baxter Healthcare South Africa (Pty) Ltd 149
    Bayer (Pty) Ltd 151
    Becton Dickinson (Pty) Ltd 154
    Bio Earth Manufacturing (Pty) Ltd 156
    Biologicals and Vaccines Institute of Southern Africa (Pty) Ltd (The) 158
    Bitek Industries (Pty) Ltd 160
    California Pharmaceuticals (Pty) Ltd 162
    Caprichem (Pty) Ltd 164
    Chemical Convertors (Pty) Ltd 167
    Chemtron Holdings (Pty) Ltd 168
    Cilo Cybin Pharmaceutical (Pty) Ltd 170
    Cipla Medpro South Africa (Pty) Ltd 172
    Columbia Pharmaceuticals (Pty) Ltd 176
    CoMED Health (Pty) Ltd 178
    Deon Schoeman CC 180
    Dis-Chem Pharmacies Ltd 182
    Dr Reddy\'s Laboratories (Pty) Ltd 193
    DSV Healthcare (Pty) Ltd 195
    Dynachem (Pty) Ltd 197
    Ecolab (Pty) Ltd 199
    Eli Lilly (S A) (Pty) Ltd 201
    Evohealth (Pty) Ltd 203
    Felbridge (Pty) Ltd 205
    Ferring (Pty) Ltd 207
    Forever Living Products South Africa (Pty) Ltd 209
    Fresenius Kabi Manufacturing SA (Pty) Ltd 212
    Fresenius Kabi South Africa (Pty) Ltd 214
    G M Pharmaceuticals (Pty) Ltd 217
    GlaxoSmithKline South Africa (Pty) Ltd 219
    Glenmark Pharmaceuticals South Africa (Pty) Ltd 222
    Goodleaf Company (Pty) Ltd (The) 224
    Gulf Drug Company (Pty) Ltd 226
    H H Durrheim (Pty) Ltd 228
    Herba Zone (Pty) Ltd 230
    Herbalife International South Africa Ltd 232
    Hersol Manufacturing Laboratories (Pty) Ltd 234
    Hymed (Pty) Ltd 236
    IMBC Investment (Pty) Ltd 238
    iMvula Healthcare Logistics (Pty) Ltd 240
    Infection Protection Products (Pty) Ltd 243
    Ingelheim Pharmaceuticals (Pty) Ltd 245
    Iszipharm Pharmaceutical Distributors (Pty) Ltd 247
    Joe Soap CC 249
    Johnson and Johnson (Pty) Ltd 251
    Kellogg Company of South Africa (Pty) Ltd 253
    Kevali Chemical Group (Pty) Ltd 255
    Lakato (Pty) Ltd 257
    Leaf Botanicals (Pty) Ltd 259
    MedCan (Pty) Ltd 260
    Medichem (Pty) Ltd 261
    Mega Magic CC 263
    Merck (Pty) Ltd 265
    MSD (Pty) Ltd 267
    National Bioproducts Institute NPC 269
    Nativa (Pty) Ltd 271
    NeoLife International (Pty) Ltd 273
    Nestle (South Africa) (Pty) Ltd 275
    Netcare Pharmacies (Pty) Ltd 279
    Netcare Pharmacies 2 (Pty) Ltd 281
    New Clicks South Africa (Pty) Ltd 283
    Nkunzi Pharmaceuticals (Pty) Ltd 286
    Novartis South Africa (Pty) Ltd 288
    Nutritional Holdings Ltd 291
    Omnia Holdings Ltd 295
    Organon South Africa (Pty) Ltd 300
    P and G South African Trading (Pty) Ltd 302
    Parceval (Pty) Ltd 304
    Pfizer Laboratories (Pty) Ltd 306
    Pharma Dynamics (Pty) Ltd 309
    Pharmaceutical Enterprises (Pty) Ltd 311
    Pharmacy Direct (Pty) Ltd 313
    Pharmacyweb Holdings (Pty) Ltd 315
    PharmaForce (Pty) Ltd 316
    Pharmed Pharmaceuticals (Pty) Ltd 318
    Pick n Pay Stores Ltd 321
    Platchem (Pty) Ltd 326
    Prime Cleaning Suppliers (Pty) Ltd 328
    Ranbaxy (S A) (Pty) Ltd 330
    Ranbaxy Pharmaceuticals (Pty) Ltd 332
    Reckitt Benckiser Pharmaceuticals (Pty) Ltd 334
    Releaf Pharmaceuticals (Pty) Ltd 336
    Richbay Chemicals (Pty) Ltd 338
    Roche Products (Pty) Ltd 341
    S A F I C (Pty) Ltd 344
    S A Natural Products (Pty) Ltd 346
    S Buys (Pty) Ltd 348
    Safarmex (Pty) Ltd 351
    Safety Chemicals (Pty) Ltd 353
    Sandoz South Africa (Pty) Ltd 355
    Sanofi Industries South Africa (Pty) Ltd 357
    Sanofi-Aventis South Africa (Pty) Ltd 359
    Shoprite Holdings Ltd 362
    Solgar South Africa (Pty) Ltd 368
    Sonke Pharmaceuticals (Pty) Ltd 370
    South African Nuclear Energy Corporation Ltd (The) 372
    SPAR Group Ltd (The) 376
    Specialised Maintenance Products (Pty) Ltd 382
    Specpharm Holdings (Pty) Ltd 383
    Spectank (Pty) Ltd 385
    Tevo (Pty) Ltd 387
    Tiger Brands Ltd 389
    Topmed Health Care Distributors (Pty) Ltd 394
    Touchless Germ Control Western Cape CC 396
    Transpharm (Pty) Ltd 397
    Unilever South Africa (Pty) Ltd 399
    Vital Health Foods (Pty) Ltd 403
    Waco Africa (Pty) Ltd 405
    Wellness Warehouse (Pty) Ltd 409
    Woolworths Holdings Ltd 413
    Xixia Pharmaceuticals (Pty) Ltd 417

    Report Coverage

    This report focuses on the manufacture of pharmaceuticals in South Africa and includes the wholesale and retail trade in pharmaceutical products. It includes information on the state and size of the sector and influencing factors including the response to coronavirus, regulation, research and development and competition. There are profiles of 122 companies including international companies operating in South Africa such as Cipla, Sanofi and Novartis, major local manufacturers such as Aspen and Adcock Ingram and retailers including Clicks and Dis-Chem. Other profiles include state-owned South African Nuclear Energy Corporation, whose subsidiary NTP Radioisotopes is one of the world’s largest producers of medical radioisotopes and radioisotope-based diagnostic imaging and therapy products, and Alpha Pharm pharmacies, the largest group of independent community pharmacies in South Africa.

    Introduction

    This report focuses on the manufacture of pharmaceuticals in South Africa and examines the wholesale and retail trade in pharmaceutical products. The domestic pharmaceutical market, which generated total revenue of approximately R56.4bn in 2019, is a supplier of essential products that improve health and save lives and has been identified by government as a strategic sector. South Africa’s antiretroviral (ARV) programme is the largest of its kind globally and the country is one of the world’s major producers of radiopharmaceuticals0F . The importance of the pharmaceutical sector has been amplified by the coronavirus pandemic, which has created an unprecedented global health crisis. South Africa produces the steroid dexamethasone, which has proved to be a game-changer in the treatment of severe coronavirus cases, and local researchers continue to play a key role in coronavirus vaccine trials. In the absence of a safe and effective vaccine, hand sanitisers and other hygiene products remain in high demand and the market continues to be flooded with products supplied by non-specialist companies.

    Strengths

    • About 70% of pharmaceutical products consumed in South Africa are locally produced.
    • South Africa is one of the world’s largest producers of radiopharmaceuticals.
    • South Africa’s HIV/Aids antiretroviral (ARV) programme is the largest of its kind in the world.
    • The presence of several of the world’s largest pharmaceutical companies facilitates knowledge sharing and supports research and product development.
    • The South African pharmaceutical industry is well developed and complies with World Health Organisation production standards.
    • There is a high standard of research and development.

    Weaknesses

    • Although pharmaceuticals are strictly regulated, over-the-counter medications and prescription drugs are widely misused and abused.
    • Quality control relating to hand sanitisers and other hygiene products.
    • The cost of medicinal products, particularly newly developed treatments such as cell and gene therapies, is high.
    • There are around 26 pharmacists per 100,000 people, well below the global benchmark of 50 per 100,000.
    • There is an overreliance on imported active pharmaceutical ingredients.

    Opportunities

    • Advances in 3D printing have made the production of small batches of tablets viable.
    • As the Department of Health expands its chronic medication delivery and collection services programme, greater collaboration between it and pharmacies is anticipated.
    • Government has identified the pharmaceutical industry as a strategic sector and it supports the procurement of locally manufactured products.
    • Strong demand for home delivery services is driving the expansion of courier pharmacy networks.
    • The development of bio-based medicinal products using locally sourced plant-based ingredients.
    • The development, production and supply of health products containing cannabidiol.
    • The National Health Insurance offers opportunities for private sector community pharmacies to provide primary care services to public health patients.
    • The supply of complementary (alternative) healthcare products via online and mobile retail channels.
    • The supply of sanitising products and disinfectants to the domestic market and to the rest of Africa.
    • With free trade between African counties set to commence in 2021, South Africa aims to expand its pharmaceutical exports into the rest of Africa.

    Threats

    • Climate change-related shocks.
    • Counterfeit medication and substandard sanitising products pose a threat to public health and safety.
    • Economic pressures could result in funding constraints.
    • Further reputational damage resulting from the misuse/abuse of prescription drugs.
    • The emergence of drug-resistant “super bugs”.
    • The pandemic could cause further supply chain disruption.
    • The resurgence of coronavirus and the emergence of new infectious diseases.

    Outlook

    Pandemic-related supply chain disruptions have highlighted the risks associated with South Africa’s overreliance on imported pharmaceutical inputs and certain finished medicinal products, amplifying the need for greater self-sufficiency. Role players have welcomed government’s commitment to support locally manufactured products and are optimistic that local manufacturers will be able to ramp up production to meet the needs of the country and the continent. South African-based pharmaceutical manufacturers are set to benefit from the creation of the African Continental Free Trade Area and, with free trade between African states scheduled to commence in 2021, role players are hoping to expand pharmaceutical exports into the rest of Africa. In the wholesale and retail markets, stakeholders predict that players will continue to explore non-traditional distribution, delivery and dispensing models. Ecommerce is expected to remain on a strong growth trajectory. With private retail pharmacies already partnering with the Department of Health to dispense antiretroviral (ARV) treatment and chronic medications to state-patients, role players anticipate a higher level of collaboration between the public and private sectors going forward. In the research and development space, stakeholders are hopeful of attracting investment for the development of new treatments and hygiene products. In the interim, the quest for safe and effective coronavirus vaccines and other treatments continues. Researchers say that until such time as a reliable vaccine has been administered to the population, hand sanitisers will remain a vital aspect of the pandemic response.

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    The Pharmaceutical Industry in South Africa 2020

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    The Pharmaceutical Industry in South Africa 2023-08-23

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    The Pharmaceutical Industry in South Africa 2022-03-08

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    The Pharmaceutical Industry in South Africa 2019-04-05

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    The Pharmaceutical Industry in South Africa 2017-12-08

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Value Chain 7
    2.2. Geographic Position 8
    3. SIZE OF THE INDUSTRY 9
    4. STATE OF THE INDUSTRY 12
    4.1. Local 12
    4.1.1. Corporate Actions 17
    4.1.2. Regulations 18
    4.1.3. Enterprise Development and Social Economic Development 24
    4.2. Continental 25
    4.3. International 28
    5. INFLUENCING FACTORS 33
    5.1. Coronavirus 33
    5.2. Government Interventions 35
    5.3. Economic Environment 37
    5.4. Labour Resources 39
    5.5. Technology, Research and Development (R&D) and Innovation 40
    5.6. Environmental Concerns 42
    5.7. Drug Abuse 42
    5.8. Substandard Products 43
    6. COMPETITION 43
    6.1. Barriers to Entry 45
    7. SWOT ANALYSIS 46
    8. OUTLOOK 47
    9. INDUSTRY ASSOCIATIONS 48
    10. REFERENCES 49
    10.1. Publications 49
    10.2. Websites 50
    APPENDIX 1 52
    Summary of Notable Players 52
    COMPANY PROFILES 64
    ABBOTT LABORATORIES SOUTH AFRICA (PTY) LTD 64
    ACINO HEALTHCARE GROUP (PTY) LTD 66
    ADCOCK INGRAM HOLDINGS LTD 69
    AFRICAN MEDICINES (PTY) LTD 74
    AFRIPLEX (PTY) LTD 76
    AIM AFRICA 79
    ALPHA PHARM (PTY) LTD 81
    AMKA PRODUCTS (PTY) LTD 83
    AMWAY SOUTH AFRICA (PTY) LTD 86
    ASCENDIS HEALTH LTD 88
    ASPEN PHARMACARE HOLDINGS LTD 94
    ASTELLAS PHARMA (PTY) LTD 100
    ASTRAZENECA PHARMACEUTICALS (PTY) LTD 102
    AUROBINDO PHARMA (PTY) LTD 104
    AUSTELL PHARMACEUTICALS (PTY) LTD 106
    B BRAUN MEDICAL (PTY) LTD 108
    BARRS PHARMACEUTICALS INDUSTRIES (PTY) LTD 111
    BAXTER HEALTHCARE SOUTH AFRICA (PTY) LTD 113
    BAYER (PTY) LTD 115
    BECTON DICKINSON (PTY) LTD 118
    BIO EARTH MANUFACTURING (PTY) LTD 120
    BIOCLONES (PTY) LTD 122
    BIOLOGICALS AND VACCINES INSTITUTE OF SOUTHERN AFRICA (PTY) LTD (THE) 124
    BITEK INDUSTRIES (PTY) LTD 126
    BRANSON CHEMICALS (PTY) LTD 128
    CALIFORNIA PHARMACEUTICALS (PTY) LTD 130
    CAPRICHEM (PTY) LTD 132
    CHEMICAL CONVERTORS (PTY) LTD 135
    CHEMTRON HOLDINGS (PTY) LTD 136
    CIPLA MEDPRO SOUTH AFRICA (PTY) LTD 137
    COLUMBIA PHARMACEUTICALS (PTY) LTD 141
    COMED HEALTH (PTY) LTD 143
    DEON SCHOEMAN CC 145
    DIS-CHEM PHARMACIES LTD 147
    DR REDDY\'S LABORATORIES (PTY) LTD 157
    DYNACHEM (PTY) LTD 159
    ECOLAB (PTY) LTD 161
    ELI LILLY (SA) (PTY) LTD 163
    EVOHEALTH (PTY) LTD 165
    FERRING (PTY) LTD 167
    FOREVER LIVING PRODUCTS SOUTH AFRICA (PTY) LTD 169
    FRESENIUS KABI MANUFACTURING SA (PTY) LTD 172
    FRESENIUS KABI SOUTH AFRICA (PTY) LTD 174
    G M PHARMACEUTICALS (PTY) LTD 177
    GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD 179
    GLENMARK PHARMACEUTICALS SOUTH AFRICA (PTY) LTD 182
    GULF DRUG COMPANY (PTY) LTD 184
    H H DURRHEIM (PTY) LTD 186
    HERBA ZONE (PTY) LTD 188
    HERBALIFE INTERNATIONAL SOUTH AFRICA LTD 190
    HERSOL MANUFACTURING LABORATORIES (PTY) LTD 192
    HYMED (PTY) LTD 194
    IMBC INVESTMENT (PTY) LTD 196
    IMVULA HEALTHCARE LOGISTICS (PTY) LTD 198
    INFECTION PROTECTION PRODUCTS (PTY) LTD 200
    INGELHEIM PHARMACEUTICALS (PTY) LTD 202
    ISZIPHARM PHARMACEUTICAL DISTRIBUTORS (PTY) LTD 204
    JOE SOAP CC 206
    JOHNSON AND JOHNSON (PTY) LTD 208
    KELLOGG COMPANY OF SOUTH AFRICA (PTY) LTD 210
    KEVALI CHEMICAL GROUP (PTY) LTD 212
    LAKATO (PTY) LTD 214
    MEDICHEM (PTY) LTD 216
    MEGA MAGIC CC 217
    MERCK (PTY) LTD 219
    MSD (PTY) LTD 221
    NATIONAL BIOPRODUCTS INSTITUTE 223
    NATIVA (PTY) LTD 225
    NEOLIFE INTERNATIONAL (PTY) LTD 227
    NESTLE (SOUTH AFRICA) (PTY) LTD 229
    NETCARE PHARMACIES (PTY) LTD 233
    NETCARE PHARMACIES 2 (PTY) LTD 235
    NEW CLICKS SOUTH AFRICA (PTY) LTD 237
    NKUNZI PHARMACEUTICALS (PTY) LTD 240
    NOVARTIS SOUTH AFRICA (PTY) LTD 242
    NUTRITIONAL HOLDINGS LTD 245
    OMNIA HOLDINGS LTD 249
    P AND G SOUTH AFRICAN TRADING (PTY) LTD 253
    PARCEVAL (PTY) LTD 255
    PFIZER LABORATORIES (PTY) LTD 257
    PHARMA DYNAMICS (PTY) LTD 260
    PHARMACEUTICAL ENTERPRISES (PTY) LTD 262
    PHARMACY DIRECT (PTY) LTD 264
    PHARMAFORCE (PTY) LTD 266
    PHARMED PHARMACEUTICALS (PTY) LTD 268
    PICK N PAY STORES LTD 271
    PLATCHEM (PTY) LTD 275
    PRIME CLEANING SUPPLIERS (PTY) LTD 277
    RANBAXY (S A) (PTY) LTD 279
    RANBAXY PHARMACEUTICALS (PTY) LTD 281
    RECKITT BENCKISER PHARMACEUTICALS (PTY) LTD 283
    RICHBAY CHEMICALS (PTY) LTD 285
    ROCHE PRODUCTS (PTY) LTD 287
    S A F I C (PTY) LTD 290
    S A NATURAL PRODUCTS (PTY) LTD 292
    S BUYS (PTY) LTD 294
    SAFARMEX (PTY) LTD 297
    SAFETY CHEMICALS (PTY) LTD 299
    SANDOZ SOUTH AFRICA (PTY) LTD 300
    SANOFI INDUSTRIES SOUTH AFRICA (PTY) LTD 302
    SANOFI-AVENTIS SOUTH AFRICA (PTY) LTD 304
    SHOPRITE HOLDINGS LTD 307
    SISONKE PARTNERSHIP (THE) 312
    SOLGAR SOUTH AFRICA (PTY) LTD 314
    SONKE PHARMACEUTICALS (PTY) LTD 316
    SOUTH AFRICAN NUCLEAR ENERGY CORPORATION SOC LTD (THE) 318
    SPAR GROUP LTD (THE) 322
    SPECIALISED MAINTENANCE PRODUCTS (PTY) LTD 328
    SPECPHARM HOLDINGS (PTY) LTD 329
    SPECTANK (PTY) LTD 331
    TEVO (PTY) LTD 333
    TIGER BRANDS LTD 335
    TOPMED HEALTH CARE DISTRIBUTORS (PTY) LTD 340
    TOUCHLESS GERM CONTROL WESTERN CAPE CC 342
    TRANSPHARM (PTY) LTD 343
    UNILEVER SOUTH AFRICA (PTY) LTD 345
    VITAL HEALTH FOODS (PTY) LTD 348
    WACO AFRICA (PTY) LTD 350
    WELLNESS WAREHOUSE (PTY) LTD 354
    WOOLWORTHS HOLDINGS LTD 357
    XIXIA PHARMACEUTICALS (PTY) LTD 361

    Report Coverage

    This report on the pharmaceutical industry describes the industry, its size, new developments and factors influencing its success. There are comprehensive profiles of 89 companies including the major manufacturers Aspen Pharmacare, Adcock Ingram and Indian manufacturer Cipla and the biggest retailers Dis-Chem and Clicks (New Clicks). Other companies profiled include Ascendis Health, which has sold its pharmaceutical manufacturing facility in Gauteng to Mylan for R130m and is assessing the sale of other divisions and units to focus the business and reduce debt.

    Introduction

    This report focuses on the pharmaceutical sector, which researches, develops, markets and distributes drugs, as part of the wider healthcare system. The industry is valued at R50bn at manufacturers’ exit price and R68bn using retail sales. The challenge facing the industry is expanding access to and affordability of drugs, on the one hand and growing South Africa’s drug manufacturing capacity on the other. The sector seeks to meet this challenge in the context of implementation of the National Health Insurance (NHI) and rapid technological developments.

    Strengths

    • Investments in capabilities to conduct clinical trials, secondary and tertiary manufacturing.
    • Many different pharmaceutical companies operating in specialised markets.
    • South Africa has a high demand for pharmaceutical products.

    Weaknesses

    • Dependence on imported active pharmaceutical ingredients and pharmaceuticals.
    • Skills shortages remain high, with 12,000 pharmacists needed to meet the international benchmarks.
    • Uncertainty over the implementation of National Health Insurance.

    Opportunities

    • Export into growing markets in Africa.
    • Improvements in regulatory environment with the South African Health Products Regulatory Authority offering an improved service.
    • Intellectual property landscape supportive of more affordable drugs and local manufacturing.
    • Local manufacturing capabilities can be leveraged to serve growing market demand in the rest of Africa and globally.

    Threats

    • Continued closures of independent pharmacies.
    • Debt in larger companies may limit expansion and may result in the closure of units or even entire businesses.
    • Increasing regulatory costs.
    • Low economic growth and currency volatility.

    Outlook

    The outlook for the pharmaceutical industry in South Africa is challenging. Since 2017, high debt in major companies has necessitated restructuring and the sale of businesses, and this process is likely to continue. Government support for pharmaceutical manufacturers, price setting for medications and investments in special economic zones represents an opportunity for the growth of local manufacturing capacity, although this is contingent on government and the private sector meeting their commitments. In providing support, government is hoping to grow local manufacture of drugs and bring down the cost of medicines. The changes to the intellectual property regime, vigilance of the Competition Commission and activism in civil society continue to point to a framework that potentially supports a reduction in drug prices and builds local manufacturing capacity.

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    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2019

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    The Pharmaceutical Industry in South Africa 2023-08-23

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    The Pharmaceutical Industry in South Africa 2022-03-08

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    The Pharmaceutical Industry in South Africa 2020-12-11

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    The Pharmaceutical Industry in South Africa 2017-12-08

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    The Pharmaceutical Industry in South Africa 2016-09-12

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Supply Chain 4
    2.2. Geographic Position 5
    3. SIZE OF THE INDUSTRY 5
    4. STATE OF THE INDUSTRY 6
    4.1. Local 6
    4.1.1. Corporate Actions 11
    4.1.2. Regulations 12
    4.1.3. Enterprise Development and Social Economic Development 14
    4.2. Continental 15
    4.3. International 15
    5. INFLUENCING FACTORS 17
    5.1. Economic Environment 17
    5.2. Labour Resources 19
    5.3. Technology, Research and Development (R&D) and Innovation 22
    5.4. Environmental Concerns 22
    6. COMPETITION 23
    6.1. Barriers to Entry 25
    7. SWOT ANALYSIS 25
    8. OUTLOOK 26
    9. INDUSTRY ASSOCIATIONS 26
    10. REFERENCES 27
    10.1. Publications 27
    10.2. Websites 28
    APPENDIX 1 30
    Summary of Notable Players 30
    COMPANY PROFILES 41
    ABBOTT LABORATORIES SOUTH AFRICA (PTY) LTD 41
    ACINO HEALTHCARE GROUP (PTY) LTD 43
    ADCOCK INGRAM HOLDINGS LTD 45
    AFRICAN MEDICINES (PTY) LTD 50
    AFRIPLEX (PTY) LTD 52
    AIM AFRICA 55
    ALPHA PHARM (KZN) (PTY) LTD 57
    ALPHA PHARM (PTY) LTD 59
    ALPHA PHARM EAST CAPE (PTY) LTD 61
    AMWAY SOUTH AFRICA (PTY) LTD 63
    ASCENDIS HEALTH LTD 66
    ASPEN PHARMACARE HOLDINGS LTD 73
    ASTELLAS PHARMA (PTY) LTD 79
    ASTRAZENECA PHARMACEUTICALS (PTY) LTD 81
    AUROBINDO PHARMA (PTY) LTD 83
    AUSTELL LABORATORIES (PTY) LTD 85
    B BRAUN MEDICAL (PTY) LTD 87
    BAXTER HEALTHCARE SOUTH AFRICA (PTY) LTD 90
    BAYER (PTY) LTD 92
    BECTON DICKINSON (PTY) LTD 95
    BIOCLONES (PTY) LTD 97
    BIOFORCE SOUTH AFRICA (PTY) LTD 99
    CALIFORNIA PHARMACEUTICALS (PTY) LTD 101
    CIPLA MEDPRO SOUTH AFRICA (PTY) LTD 103
    COLUMBIA PHARMACEUTICALS (PTY) LTD 107
    COMED HEALTH (PTY) LTD 109
    DEON SCHOEMAN CC 111
    DIS-CHEM PHARMACIES LTD 113
    DR REDDY\'S LABORATORIES (PTY) LTD 122
    ELI LILLY (SA) (PTY) LTD 124
    FERRING (PTY) LTD 126
    FOREVER LIVING PRODUCTS SOUTH AFRICA (PTY) LTD 128
    FRESENIUS KABI MANUFACTURING SA (PTY) LTD 131
    FRESENIUS KABI SOUTH AFRICA (PTY) LTD 133
    G M PHARMACEUTICALS (PTY) LTD 136
    GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD 138
    GULF DRUG COMPANY (PTY) LTD 141
    H H DURRHEIM (PTY) LTD 143
    HERBA ZONE (PTY) LTD 145
    HERBALIFE INTERNATIONAL SOUTH AFRICA LTD 147
    HERSOL MANUFACTURING LABORATORIES (PTY) LTD 149
    IMBC INVESTMENT (PTY) LTD 151
    IMVULA HEALTHCARE LOGISTICS (PTY) LTD 153
    INGELHEIM PHARMACEUTICALS (PTY) LTD 156
    JOHNSON AND JOHNSON (PTY) LTD 158
    KELLOGG COMPANY OF SOUTH AFRICA (PTY) LTD 160
    LAKATO (PTY) LTD 162
    MERCK (PTY) LTD 164
    MSD (PTY) LTD 166
    NATIONAL BIOPRODUCTS INSTITUTE 168
    NATIVA (PTY) LTD 170
    NEOLIFE INTERNATIONAL (PTY) LTD 172
    NESTLE (SOUTH AFRICA) (PTY) LTD 174
    NETCARE PHARMACIES (PTY) LTD 178
    NETCARE PHARMACIES 2 (PTY) LTD 180
    NEW CLICKS SOUTH AFRICA (PTY) LTD 182
    NKUNZI PHARMACEUTICALS (PTY) LTD 185
    NOVARTIS SOUTH AFRICA (PTY) LTD 187
    NUTRITIONAL HOLDINGS LTD 190
    OMNIA HOLDINGS LTD 193
    P AND G SOUTH AFRICAN TRADING (PTY) LTD 197
    PARCEVAL (PTY) LTD 199
    PFIZER LABORATORIES (PTY) LTD 201
    PHARMA DYNAMICS (PTY) LTD 204
    PHARMACEUTICAL ENTERPRISES (PTY) LTD 206
    PHARMACY DIRECT (PTY) LTD 208
    PHARMED PHARMACEUTICALS (PTY) LTD 210
    PICK N PAY STORES LTD 213
    RANBAXY (S A) (PTY) LTD 218
    RANBAXY PHARMACEUTICALS (PTY) LTD 220
    ROCHE PRODUCTS (PTY) LTD 222
    S A NATURAL PRODUCTS (PTY) LTD 225
    S BUYS (PTY) LTD 227
    SANDOZ SOUTH AFRICA (PTY) LTD 230
    SANOFI INDUSTRIES SOUTH AFRICA (PTY) LTD 233
    SANOFI-AVENTIS SOUTH AFRICA (PTY) LTD 235
    SHOPRITE HOLDINGS LTD 238
    SISONKE PARTNERSHIP (THE) 242
    SOLGAR SOUTH AFRICA (PTY) LTD 244
    SONKE PHARMACEUTICALS (PTY) LTD 246
    SOUTH AFRICAN NUCLEAR ENERGY CORPORATION SOC LTD (THE) 248
    SPAR GROUP LTD (THE) 252
    SPECPHARM HOLDINGS (PTY) LTD 257
    TIGER BRANDS LTD 259
    TRANSPHARM (PTY) LTD 264
    VITAL HEALTH FOODS (PTY) LTD 266
    WELLNESS WAREHOUSE (PTY) LTD 268
    XIXIA PHARMACEUTICALS (PTY) LTD 271
    ZENITH PHARMACEUTICAL DISTRIBUTORS (PTY) LTD 273

    Report Coverage

    The detailed report on the Pharmaceutical industry focuses on developments in the South African manufacturing and retail sectors during 2016 and 2017. The report profiles 88 companies including newcomer Inicio, which recently secured a licensing agreement with German firm Fluxpharm. The agreement is a key step towards possible domestic production of active pharmaceutical ingredients (APIs) for HIV/AIDS drugs, which locally-based pharmaceutical manufacturers currently import from China and India. If this is successful, South Africa will have its first black-owned pharmaceutical company. State-owned pharmaceutical manufacturer Ketlaphela has yet to begin production of APIs. Also profiled are three companies that have been investigated by the Competition Commission in relation to the supply of various cancer medicines, Pfizer, Aspen and Roche and its US-based biotechnology company, Genentech.

    Introduction

    This report focuses on developments in the South African pharmaceutical industry during 2016 and 2017. The pharmaceutical industry provides the vital service of providing medication and was valued at R42.6bn in 2016. The most important challenges facing the industry are tensions between improving access to affordable medicines on the one hand, and growing the manufacturing of pharmaceuticals on the other. Other factors influencing the sector include the introduction of the National Health Insurance (NHI), significant changes in technologies to manufacture drugs and the emergence of the use of cannabis and other alternative healing methods.

    Strengths

    • Improving levels of local manufacturing capacity.
    • Investments in capabilities to conduct clinical trials, secondary and tertiary manufacturing.
    • Many different pharmaceutical companies operating in specialised markets.
    • South Africa has a high demand for pharmaceutical products.

    Weaknesses

    • Dependence on imported APIs and pharmaceuticals.
    • Single Exit Price (SEP) mechanism means manufacturers are pressurised as far as pricing is concerned.
    • Skills shortages remain high, with 12,000 pharmacists needed to meet international benchmarks.

    Opportunities

    • Export into growing markets in Africa.
    • Improvements in regulatory environment with the launch of the South African Health Products Regulatory Authority (SAHPRA).
    • Improvements in the Intellectual Property (IP) landscape.
    • Local manufacturing capabilities can be leveraged to serve growing market demand in the rest of Africa and globally.
    • The establishment of API manufacturing sites.
    • The state pharmaceutical company, Ketlaphela, could reduce prices and support research once it is operational.

    Threats

    • Continued closures of independent pharmacies.
    • Increasing regulatory costs.
    • Low economic growth and currency volatility.
    • The legalisation of cannabis as a natural medication.

    Outlook

    Growth in the pharmaceutical industry is likely to continue, but at a slower pace than experienced over the last five years. Role players believe that the South African pharmaceutical industry will continue to experience major changes mainly in meeting the objectives of providing affordable drugs and at the same time growing manufacturing capacity. Reaching these objectives will prove difficult because of the low levels of economic growth, with stakeholders expressing concern regarding the impact this will have on government resources in general, and specifically on the implementation of the NHI. The interaction between an organised civil society lobbying for affordable drugs, and an organised established pharmaceutical sector seeking to protect its patent laws, is expected to play a significant role in determining the future of the pharmaceutical industry in South Africa.

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    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2017

    Full Report

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    Industry Landscape

    R 1 330.00(ZAR) estimated $ 75.29 (USD)*

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    The Pharmaceutical Industry in South Africa 2025-07-15

    R 20 000.00(ZAR) estimated $1132.11 (USD)*

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    The Pharmaceutical Industry in South Africa 2023-08-23

    R 6 500.00(ZAR) estimated $367.94 (USD)*

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    The Pharmaceutical Industry in South Africa 2022-03-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2020-12-11

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2019-04-05

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2016-09-12

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2014-05-30

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Value Chain 4
    2.2. Geographic Position 5
    3. SIZE OF THE INDUSTRY 6
    4. STATE OF THE INDUSTRY 17
    4.1. Local 17
    4.1.1. Corporate Actions 20
    4.1.2. Regulations 21
    4.1.3. Enterprise Development and Social Economic Development 24
    4.2. Continental 25
    4.3. International 26
    5. INFLUENCING FACTORS 28
    5.1. Economic Environment 28
    5.2. Labour 29
    5.3. Technology, Research and Development (R&D) and Innovation 31
    5.4. Environmental Concerns 31
    6. COMPETITION 32
    6.1. Barriers to Entry 34
    7. SWOT ANALYSIS 34
    8. OUTLOOK 35
    9. INDUSTRY ASSOCIATIONS 36
    10. REFERENCES 37
    10.1. Publications 37
    10.2. Websites 37
    COMPANY PROFILES 38
    ABBOTT LABORATORIES SOUTH AFRICA (PTY) LTD 38
    ADCOCK INGRAM HOLDINGS LTD 40
    AFRICAN MEDICINES (PTY) LTD 45
    AFRIPLEX (PTY) LTD 47
    AIM AFRICA 50
    ALPHA PHARM (KZN) (PTY) LTD 52
    ALPHA PHARM (PTY) LTD 54
    ALPHA PHARM EAST CAPE (PTY) LTD 56
    AMWAY SOUTH AFRICA (PTY) LTD 58
    ASCENDIS HEALTH LTD 60
    ASPEN PHARMACARE HOLDINGS LTD 67
    ASTELLAS PHARMA (PTY) LTD 72
    ASTRAZENECA PHARMACEUTICALS (PTY) LTD 74
    AUROBINDO PHARMA (PTY) LTD 76
    AUSTELL LABORATORIES (PTY) LTD 78
    B BRAUN MEDICAL (PTY) LTD 80
    BAXTER HEALTHCARE SOUTH AFRICA (PTY) LTD 83
    BAYER (PTY) LTD 85
    BECTON DICKINSON (PTY) LTD 88
    BIOCLONES (PTY) LTD 90
    CALIFORNIA PHARMACEUTICALS (PTY) LTD 92
    CIPLA MEDPRO SOUTH AFRICA (PTY) LTD 94
    COLUMBIA PHARMACEUTICALS (PTY) LTD 98
    COMED HEALTH (PTY) LTD 100
    DEON SCHOEMAN CC 102
    DIS-CHEM PHARMACIES LTD 104
    DR REDDY\'S LABORATORIES (PTY) LTD 113
    ELI LILLY (SA) (PTY) LTD 115
    FERRING (PTY) LTD 117
    FOREVER LIVING PRODUCTS SOUTH AFRICA (PTY) LTD 119
    FRESENIUS KABI MANUFACTURING SA (PTY) LTD 122
    FRESENIUS KABI SOUTH AFRICA (PTY) LTD 124
    G M PHARMACEUTICALS (PTY) LTD 127
    GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD 129
    GULF DRUG COMPANY (PTY) LTD 132
    H H DURRHEIM (PTY) LTD 134
    HERBA ZONE (PTY) LTD 136
    HERBALIFE INTERNATIONAL SOUTH AFRICA LTD 138
    HERSOL MANUFACTURING LABORATORIES (PTY) LTD 140
    IMBC INVESTMENT (PTY) LTD 142
    IMVULA HEALTHCARE LOGISTICS (PTY) LTD 144
    INGELHEIM PHARMACEUTICALS (PTY) LTD 146
    JOHNSON AND JOHNSON (PTY) LTD 148
    KELLOGG COMPANY OF SOUTH AFRICA (PTY) LTD 151
    LAKATO (PTY) LTD 153
    LITHA HEALTHCARE GROUP (PTY) LTD 155
    MERCK (PTY) LTD 157
    MSD (PTY) LTD 159
    NATIONAL BIOPRODUCTS INSTITUTE 161
    NATIVA (PTY) LTD 163
    NEOLIFE INTERNATIONAL (PTY) LTD 165
    NESTLE (SOUTH AFRICA) (PTY) LTD 167
    NETCARE PHARMACIES 2 (PTY) LTD 171
    NEW CLICKS SOUTH AFRICA (PTY) LTD 173
    NKUNZI PHARMACEUTICALS (PTY) LTD 176
    NOVARTIS SOUTH AFRICA (PTY) LTD 178
    NUTRI PHARMA SOLUTIONS (PTY) LTD 180
    NUTRITIONAL HOLDINGS LTD 182
    OMNIA HOLDINGS LTD 185
    PARCEVAL (PTY) LTD 189
    PFIZER LABORATORIES (PTY) LTD 191
    PHARMA DYNAMICS (PTY) LTD 194
    PHARMACEUTICAL ENTERPRISES (PTY) LTD 197
    PHARMACY DIRECT (PTY) LTD 199
    PHARMED PHARMACEUTICALS (PTY) LTD 201
    PICK N PAY STORES LTD 204
    PROCTER AND GAMBLE SA (PTY) LTD 209
    RANBAXY (SA) (PTY) LTD 211
    RANBAXY PHARMACEUTICALS (PTY) LTD 213
    ROCHE PRODUCTS (PTY) LTD 215
    S A NATURAL PRODUCTS (PTY) LTD 218
    S BUYS (PTY) LTD 220
    SANDOZ SOUTH AFRICA (PTY) LTD 223
    SANOFI-AVENTIS SOUTH AFRICA (PTY) LTD 226
    SHOPRITE HOLDINGS LTD 229
    SISONKE PARTNERSHIP (THE) 233
    SOLGAR SOUTH AFRICA (PTY) LTD 235
    SONKE PHARMACEUTICALS (PTY) LTD 237
    SOUTH AFRICAN NUCLEAR ENERGY CORPORATION SOC LTD (THE) 239
    SPAR GROUP LTD (THE) 242
    SPECPHARM HOLDINGS (PTY) LTD 247
    TIGER BRANDS LTD 249
    TRANSPHARM (PTY) LTD 254
    VITAL HEALTH FOODS (PTY) LTD 256
    WELLNESS WAREHOUSE (PTY) LTD 259
    XIXIA PHARMACEUTICALS (PTY) LTD 262
    ZENITH PHARMACEUTICAL DISTRIBUTORS (PTY) LTD 264
    ZENTIVA SOUTH AFRICA (PTY) LTD 266

    Report Coverage

    The report on the Pharmaceutical industry describes merger and acquisition activity, the latest regulatory developments and discusses factors influencing the success of the sector. The report profiles 90 companies ranging from South Africa’s two largest pharmaceutical manufacturers, Aspen Pharmacare and Adcock Ingram to newcomers to the Top 20, Mylan and Valeant Pharmaceuticals which both have less than 2% share of the market. Also profiled are African Medicines (Pty) Ltd t/a Pakmed Self Medication and GNLD International (Pty) Ltd, companies that use the services of contract manufacturers such as Wrapsa. Large national retailers with in-house pharmacies like Clicks and Pick ‘n Pay, which have proved to be fierce competition to traditional independent and community pharmacies, are also profiled in this report.

    Introduction

    This report focuses on developments in the South African pharmaceutical industry during 2015 and 2016. This vital industry, which incorporates research and development, manufacture, import, distribution, wholesale and retail of pharmaceutical products, was valued at R39.3bn in 2015, with total counting units reaching 51.9 billion. Although pharmaceutical companies acknowledge that their primary responsibility is to ensure access to affordable healthcare for consumers, some stakeholders, especially those campaigning for a change in the patent laws and in the private healthcare sector, believe companies continue to place large profits before improved health.

    Strengths

    • Active government support for industrialisation efforts.
    • Strong and active civil society organisations focused on improving access to and affordability of drugs.
    • There is a strong pharmaceutical R&D and clinical trial sector.
    • Well established local industry, with strong international presence.

    Weaknesses

    • Currently, dependence on MCC and a long registration period for pharmaceutical products.
    • Dependence on imported APIs and pharmaceuticals.
    • Patent system for drugs consistently challenged due to high cost of pharmaceuticals.
    • SEP regulation which does not allow manufacturers to increase prices to adjust for higher input costs.
    • Shortage of pharmacists and pharmacist assistants.

    Opportunities

    • Export into growing markets in Africa.
    • Growth of generic sector.
    • Improvements in procurement systems for public sector drug provision.
    • Improvements in regulatory environment with the imminent launch of the South African Health Products Regulatory Authority.
    • R&D, particularly the “Farmer to Pharma grand challenge.”
    • Well-functioning state-run pharmaceutical company could reduce prices and potentially support research.

    Threats

    • Continued closures of independent pharmacies.
    • Low economic growth and currency volatility.
    • Regulatory costs are high for alternative and complementary medicines.

    Outlook

    The South African pharmaceutical industry is expected to experience significant changes over the next few years. These changes include the introduction of a new regulator, the South African Health Products Regulatory Authority (SAHPRA), the implementation of the National Health Insurance and continued focus on industrialisation efforts in the pharmaceutical industry. These developments coupled with a strong civil society advocacy for changing the patent laws, are likely to create an environment that is ripe for change. These changes potentially provide South Africa with a basis to grow the pharmaceutical industry and at the same time reduce the costs of drugs. The growth of the generics segment of the market in particular is likely to provide a basis for growing manufacturing capacity, and at the same time increasing access to life-savings drugs. Stakeholders assert, however, that industry and government will need to cooperate on these matters, as the reforms being undertaken are large and carry with them significant challenges.

    Read More..
    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2016

    Full Report

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    Industry Landscape

    R 1 330.00(ZAR) estimated $ 75.29 (USD)*

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    Historical Reports

    The Pharmaceutical Industry in South Africa 2025-07-15

    R 20 000.00(ZAR) estimated $1132.11 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2023-08-23

    R 6 500.00(ZAR) estimated $367.94 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2022-03-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2020-12-11

    R 1 900.00(ZAR) estimated $107.55 (USD)*

    View Report Add to Cart

    The Pharmaceutical Industry in South Africa 2019-04-05

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2017-12-08

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    The Pharmaceutical Industry in South Africa 2014-05-30

    R 1 900.00(ZAR) estimated $107.55 (USD)*

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    Table of Contents

    [ Close ]
    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Value Chain 2
    2.2. Geographic Position 4
    3. SIZE OF THE INDUSTRY 4
    4. STATE OF THE INDUSTRY 16
    4.1. Local 16
    4.1.1. Corporate Actions 18
    4.1.2. Regulations 20
    4.1.3. Enterprise Development and Social Economic Development 23
    4.2. Continental 23
    4.3. International 25
    5. INFLUENCING FACTORS 27
    5.1. Changes to the Regulatory Environment 27
    5.2. Economic Environment 27
    5.3. Government Initiatives 28
    5.4. Technology, Research and Development (R&D) and Innovation 29
    5.5. Labour 29
    6. COMPETITION 32
    6.1. Barriers to Entry 33
    7. SWOT ANALYSIS 34
    8. OUTLOOK 35
    9. INDUSTRY ASSOCIATIONS 35
    10. REFERENCES 36
    10.1. Publications 36
    10.2. Websites 36
    APPENDIX 1 38
    List of Mergers and Acquisitions in the Global Pharmaceutical Industry in 2015 and 2016 38
    COMPANY PROFILES – MANUFACTURE AND WHOLESALE OF PHARMACEUTICALS AND NUTRICEUTICALS 50
    ABBOTT LABORATORIES SOUTH AFRICA (PTY) LTD 50
    ADCOCK INGRAM HOLDINGS LTD 52
    AFRICAN MEDICINES (PTY) LTD 57
    AFRIPLEX (PTY) LTD 59
    AIM AFRICA 62
    ALPHA PHARM (KZN) (PTY) LTD 64
    ALPHA PHARM (PTY) LTD 66
    ALPHA PHARM EAST CAPE (PTY) LTD 68
    AMWAY SOUTH AFRICA (PTY) LTD 70
    ASCENDIS HEALTH LTD 72
    ASPEN PHARMACARE HOLDINGS LTD 78
    ASTELLAS PHARMA (PTY) LTD 82
    ASTRAZENECA PHARMACEUTICALS (PTY) LTD 84
    AUROBINDO PHARMA (PTY) LTD 87
    AUSTELL LABORATORIES (PTY) LTD 89
    B BRAUN MEDICAL (PTY) LTD 91
    BAYER (PTY) LTD 95
    BECTON DICKINSON (PTY) LTD 98
    BIOCLONES (PTY) LTD 100
    CALIFORNIA PHARMACEUTICALS (PTY) LTD 102
    CIPLA MEDPRO SOUTH AFRICA (PTY) LTD 104
    COLUMBIA PHARMACEUTICALS (PTY) LTD 108
    COMED HEALTH (PTY) LTD 110
    CREST CHEMICALS (PTY) LTD 112
    DB FINE CHEMICALS (PTY) LTD 114
    DEON SCHOEMAN CC 116
    DIS-CHEM PHARMACIES (PTY) LTD 118
    DR REDDY\'S LABORATORIES (PTY) LTD 123
    ELI LILLY (SA) (PTY) LTD 125
    FERRING (PTY) LTD 127
    FOREVER LIVING PRODUCTS SOUTH AFRICA (PTY) LTD 129
    FRESENIUS KABI MANUFACTURING SA (PTY) LTD 132
    G M PHARMACEUTICALS (PTY) LTD 134
    GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD 136
    GNLD INTERNATIONAL (PTY) LTD 138
    GULF DRUG COMPANY (PTY) LTD 140
    H H DURRHEIM (PTY) LTD 142
    HERBA ZONE (PTY) LTD 144
    HERBALIFE INTERNATIONAL SOUTH AFRICA LTD 146
    HERSOL MANUFACTURING LABORATORIES (PTY) LTD 148
    IMBC INVESTMENT (PTY) LTD 150
    IMVULA HEALTHCARE LOGISTICS (PTY) LTD 152
    INGELHEIM PHARMACEUTICALS (PTY) LTD 155
    JOHNSON AND JOHNSON (PTY) LTD 157
    KELLOGG COMPANY OF SOUTH AFRICA (PTY) LTD 160
    LAKATO (PTY) LTD 162
    LITHA HEALTHCARE GROUP (PTY) LTD 164
    MERCK (PTY) LTD 167
    MSD (PTY) LTD 169
    NATIONAL BIOPRODUCTS INSTITUTE 171
    NATIVA (PTY) LTD 173
    NESTLE (SOUTH AFRICA) (PTY) LTD 175
    NEW CLICKS SOUTH AFRICA (PTY) LTD 178
    NKUNZI PHARMACEUTICALS (PTY) LTD 181
    NOVARTIS SOUTH AFRICA (PTY) LTD 183
    NUTRI PHARMA SOLUTIONS (PTY) LTD 186
    NUTRITIONAL HOLDINGS LTD 188
    OMNIA HOLDINGS LTD 191
    PARCEVAL (PTY) LTD 195
    PFIZER LABORATORIES (PTY) LTD 197
    PHARMA DYNAMICS (PTY) LTD 200
    PHARMACEUTICAL ENTERPRISES (PTY) LTD 202
    PHARMACY DIRECT (PTY) LTD 204
    PHARMED PHARMACEUTICALS (PTY) LTD 206
    PROCTER AND GAMBLE SA (PTY) LTD 209
    RANBAXY (SA) (PTY) LTD 211
    ROCHE PRODUCTS (PTY) LTD 213
    S A NATURAL PRODUCTS (PTY) LTD 216
    S BUYS (PTY) LTD 218
    SANDOZ SOUTH AFRICA (PTY) LTD 220
    SANOFI-AVENTIS SOUTH AFRICA (PTY) LTD 222
    SAVANNAH FINE CHEMICALS (PTY) LTD 224
    SHOPRITE HOLDINGS LTD 226
    SISONKE PARTNERSHIP (THE) 232
    SK CHEMTRADE SERVICES (PTY) LTD 234
    SOLGAR SOUTH AFRICA (PTY) LTD 236
    SONKE PHARMACEUTICALS (PTY) LTD 238
    SOUTH AFRICAN NUCLEAR ENERGY CORPORATION SOC LTD (THE) 240
    SPECPHARM HOLDINGS (PTY) LTD 243
    TIGER BRANDS LTD 245
    TRANSPHARM (PTY) LTD 250
    VITAL HEALTH FOODS (PTY) LTD 252
    WARREN CHEM SPECIALITIES (PTY) LTD 255
    XIXIA PHARMACEUTICALS (PTY) LTD 257
    ZENITH PHARMACEUTICAL DISTRIBUTORS (PTY) LTD 259
    ZENTIVA SOUTH AFRICA (PTY) LTD 261
    COMPANY PROFILES - RETAIL OF PHARMACEUTICALS 263
    AIM AFRICA 263
    CLICKS RETAILERS (PTY) LTD 265
    DEON SCHOEMAN CC 267
    DIS-CHEM PHARMACIES (PTY) LTD 269
    G M PHARMACEUTICALS (PTY) LTD 275
    NATIVA (PTY) LTD 277
    NETCARE PHARMACIES 2 (PTY) LTD 279
    NEW CLICKS SOUTH AFRICA (PTY) LTD 281
    PICK N PAY STORES LTD 284
    SANDOZ SOUTH AFRICA (PTY) LTD 288
    SHOPRITE HOLDINGS LTD 290
    SPAR GROUP LTD (THE) 296
    WELLNESS WAREHOUSE (PTY) LTD 301

    Introduction

    This report focuses on the South African pharmaceutical industry. The manufacturing industry generated R32.4bn while the retail industry in pharmaceutical and medical goods, cosmetics and toiletries reached R49.96bn in 2013. Generic drug use is increasing rapidly, driven by government’s goal for more affordable pharmaceuticals in South Africa. The domestic manufacturing industry is relatively small and 65% of pharmaceuticals are imported. Medical aids have increasing power, shaping consumer use of pharmaceuticals to the advantage of corporate pharmacies, which have been able to grow their share of the market to 35.5% since 2004.

    Strengths

    • Pharmaceuticals are a vital part of the healthcare system.
    • The two leading pharmaceutical companies are locallybased,\ngeneric manufacturers.
    • There are a variety of different types of pharmaceutical\ncompanies present in the country.
    • There is a strong pharmaceutical R&D and clinical trial sector.

    Weaknesses

    • Critical skill shortage of pharmacists and pharmacist\nassistants.
    • Dependence on imported APIs and pharmaceuticals.
    • Dependence on MCC and a long registration period for\npharmaceutical products.
    • SEP regulation which does not allow manufacturers to increase prices to adjust for higher input costs

    Opportunities

    • Establishment of SAHPRA which is to replace the MCC.
    • Increasing roll-out of government tenders for generic drugs\nto treat HIV/AIDS and TB.
    • NHI through which a large number of South Africans will be\ngiven access to pharmaceuticals.
    • Opportunities for API and pharmaceutical manufacturing\nexist.
    • Patent expiry opens the market for the development of\ngenerics.
    • Potential for generic manufacturers to utilise their spare\ncapacity to produce products to export globally.
    • Potential for increased exports to African countries.

    Threats

    • Continuing delays in the registration of pharmaceutical product at the MCC.
    • Deteriorating economic conditions.
    • For community pharmacists, the practice of DSP.
    • Increasing number of cheap imports from India and China.
    • New regulations for complementary and alternative medicines will mean high costs which may be prohibitive for small companies.
    • Rising input costs, especially rising cost of imported APIs.

    Outlook

    The growth in the global pharmaceutical industry is expected to be between 3% and 6% CAGR, reaching a value of approximately $1.2 trillion in 2016. For the local industry, growth is expected because of increasing government support for the use and manufacture of pharmaceuticals. The future is “very positive from a generic point of view” according to Vivian Frittelli, CEO of the National Association of Pharmaceutical Manufacturers and the generic manufacturing industry is expected to grow by 10% in 2014 and 10% to 12% annually up to 2019. This is because of government’s increasing support for the use of generics for the treatment of HIV/AIDS and TB and the expiry of the patents for a number of originator drugs. In the short term, however, the deteriorating macroeconomic outlook is likely to slow the consumption of pharmaceuticals in the private healthcare and retail pharmaceutical sector and impact on the costs of imported ingredients and products. Manufacturers are therefore likely to look for opportunities outside South Africa to drive volumes and profits.

    The Pharmaceutical Industry in South Africa
    The Pharmaceutical Industry in South Africa 2014

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    Table of Contents

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    PAGE
    1. INTRODUCTION 1
    2. DESCRIPTION OF THE INDUSTRY 1
    2.1. Industry Supply Chain 2
    3. SIZE OF THE INDUSTRY 2
    4. STATE OF THE INDUSTRY 17
    4.1. Local 17
    4.1.1. Manufacture and Distribution/Wholesale 17
    4.1.2. Retail 19
    4.1.3. Corporate Actions 19
    4.1.4. Regulations 20
    4.1.5. Black Economic Empowerment 22
    4.2. Continental 22
    4.3. International 24
    5. INFLUENCING FACTORS 24
    5.1. SEP 24
    5.2. Intellectual Property Law 25
    5.3. Slow Registration Process for New Pharmaceuticals 25
    5.4. Medical Aids 25
    5.5. National Health Insurance (NHI) 26
    5.6. Economic Environment 26
    5.7. Disease Burden 26
    5.8. New regulations for Complementary Medicines 26
    5.9. Counterfeit Medicine 26
    5.10. Labour Resources 27
    5.11. Environmental Concerns 27
    6. COMPETITION 28
    6.1. Barriers to Entry 28
    6.2. Research and Development (R&D) and Innovation 28
    7. SWOT ANALYSIS 30
    8. OUTLOOK 30
    9. INDUSTRY ASSOCIATIONS 31
    10. REFERENCES 31
    10.1. Publications 31
    10.2. Websites 32
    ORGANOGRAM 33530 33
    Manufacture of Pharmaceuticals and Nutriceuticals 33
    COMPANY PROFILES 39
    ABBOTT LABORATORIES SOUTH AFRICA (PTY) LTD 39
    ADCOCK INGRAM HEALTHCARE (PTY) LTD 40
    AFRICAN MEDICINES (PTY) LTD 42
    AFRIPLEX (PTY) LTD 43
    AIM AFRICA INC 44
    AMWAY SOUTH AFRICA (PTY) LTD 45
    ASCENDIS HEALTH LTD 46
    ASPEN PHARMACARE HOLDINGS LTD 48
    ASTELLAS PHARMA (PTY) LTD 51
    ASTRAZENECA PHARMACEUTICALS (PTY) LTD 52
    AUROBINDO PHARMA (PTY) LTD 54
    AUSTELL LABORATORIES (PTY) LTD 55
    B BRAUN MEDICAL (PTY) LTD 56
    BAYER (PTY) LTD 58
    BIOCLONES (PTY) LTD 60
    CALIFORNIA PHARMACEUTICALS (PTY) LTD 61
    CHEMPURE (PTY) LTD 62
    CIPLA MEDPRO SOUTH AFRICA (PTY) LTD 63
    CLICKS GROUP LTD 66
    COLUMBIA PHARMACEUTICALS (PTY) LTD 69
    COMED HEALTH (PTY) LTD 70
    COVIDIEN (PTY) LTD 72
    CREST CHEMICALS (PTY) LTD 73
    DB FINE CHEMICALS (PTY) LTD 75
    DEON SCHOEMAN CC 76
    DIS-CHEM CONSOLIDATED (PTY) LTD 77
    DR REDDY\'S LABORATORIES (PTY) LTD 78
    FERRING (PTY) LTD 79
    FOREVER LIVING PRODUCTS SOUTH AFRICA (PTY) LTD 80
    FRESENIUS KABI MANUFACTURING SA (PTY) LTD 82
    GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD 83
    GM PHARMACEUTICALS (PTY) LTD 85
    GNLD INTERNATIONAL (PTY) LTD 86
    GULF DRUG COMPANY (PTY) LTD 87
    HERBA ZONE (PTY) LTD 88
    HERBALIFE INTERNATIONAL SOUTH AFRICA LTD 89
    HERSOL MANUFACTURING LABORATORIES (PTY) LTD 90
    INGELHEIM PHARMACEUTICALS (PTY) LTD 91
    JOHNSON & JOHNSON (PTY) LTD 92
    KELLOGG COMPANY OF SOUTH AFRICA (PTY) LTD 94
    LITHA HEALTHCARE GROUP LTD 95
    MERCK (PTY) LTD 97
    MSD (PTY) LTD 98
    NATIVA (PTY) LTD 99
    NESTLE (SA) (PTY) LTD 100
    NKUNZI PHARMACEUTICALS (PTY) LTD 102
    NOVARTIS SOUTH AFRICA (PTY) LTD 103
    NUTRI PHARMA SOLUTIONS (PTY) LTD 105
    NUTRITIONAL HOLDINGS LTD 106
    OMNIA HOLDINGS LTD 108
    PARCEVAL (PTY) LTD 110
    PFIZER LABORATORIES (PTY) LTD 111
    PHARMA DYNAMICS (PTY) LTD 113
    PHARMA NATURA (PTY) LTD 115
    PHARMACEUTICAL ENTERPRISES (PTY) LTD 116
    RANBAXY (SA) (PTY) LTD 117
    REGAL NUTRIENTS (PTY) LTD 119
    ROCHE PRODUCTS (PTY) LTD 120
    SA NATURAL PRODUCTS (PTY) LTD 122
    SANDOZ SOUTH AFRICA (PTY) LTD 123
    SANOFI-AVENTIS SOUTH AFRICA (PTY) LTD 124
    SAVANNAH FINE CHEMICALS (PTY) LTD 126
    SK CHEMTRADE SERVICES (PTY) LTD 127
    SOLGAR SOUTH AFRICA (PTY) LTD 128
    SONKE PHARMACEUTICALS (PTY) LTD 129
    SOUTH AFRICAN NUCLEAR ENERGY CORPORATION SOC LTD (THE) 130
    SPECPHARM HOLDINGS (PTY) LTD 132
    SPORTRON INTERNATIONAL (PTY) LTD 133
    SUNRIDER SOUTH AFRICA (PTY) LTD 134
    SWISSGARDE (PTY) LTD 135
    TIGER BRANDS LTD 136
    VITAL HEALTH FOODS (PTY) LTD 139
    WARREN CHEM SPECIALITIES (PTY) LTD 141
    WINTHROP PHARMACEUTICALS (PTY) LTD 142
    ORGANOGRAM 61394A 143
    Wholesale of Pharmaceuticals 143
    COMPANY PROFILES 145
    ALPHA PHARM (KZN) (PTY) LTD 145
    ALPHA PHARM EAST CAPE (PTY) LTD 146
    ALPHA PHARM WESTERN CAPE LTD 147
    BECTON DICKINSON (PTY) LTD 148
    CHERYL HAWKINS SOLE PROPRIETOR 152
    CLICKS GROUP LTD 153
    DIS-CHEM PHARMACIES (PTY) LTD 156
    ELI LILLY (SA) (PTY) LTD 159
    FREE STATE BUYING ASSOCIATION LTD 160
    HH DURRHEIM (PTY) LTD 161
    IMBC INVESTMENT (PTY) LTD 163
    IMVULA HEALTHCARE LOGISTICS (PTY) LTD 164
    LAKATO (PTY) LTD 166
    NAMPAK PRODUCTS LTD 167
    P&G SOUTH AFRICAN TRADING (PTY) LTD 170
    PHARMACY DIRECT (PTY) LTD 171
    PHARMED PHARMACEUTICALS (PTY) LTD 172
    PREMIER FOODS (PTY) LTD 174
    RTT GROUP (PTY) LTD 176
    SISONKE PARTNERSHIP (THE) 179
    TRANSPHARM (PTY) LTD 181
    UTI SOUTH AFRICA (PTY) LTD 182
    XIXIA PHARMACEUTICALS (PTY) LTD 185
    ZENITH PHARMACEUTICAL DISTRIBUTORS (PTY) LTD 186
    ORGANOGRAM 62310A 187
    Retail of Pharmaceuticals 187
    COMPANY PROFILES 188
    CHRONIC MEDICINE DISPENSARY (PTY) LTD 188
    CLICKS DIRECT MEDICINES (PTY) LTD 189
    CLICKS GROUP LTD 190
    DIS-CHEM PHARMACIES (PTY) LTD 193
    NETCARE PHARMACIES 2 (PTY) LTD 196
    PICK \'N PAY STORES LTD 197
    S BUYS (PTY) LTD 220
    SHOPRITE HOLDINGS LTD 222
    SPAR GROUP LTD (THE) 226
    WELLNESS WAREHOUSE (PTY) LTD 229

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